Probably not. But here's the thing: it is on the 7ECA type cert (see item 125) and 7ECAs are probably the most underpriced lightplane out there for what they are.
Let's say your Champ would sell for $25K and you can find a 7ECA with good O-320 for $40K. That cost you $15K plus use tax. You would probably have to pay 15 for a good used O-320 anyway, and then buy the STC, modify the airframe, get new exhaust, cowl, etc., and if you are not s mechanic, pay someone two weeks' labor. Sounds like a real lose-lose proposition.
But hanging a 150 hp engine on an airframe designed for a C-90 is probably not a good idea even if you could get approval.